Objective To explore the post-traumatic growth（PTG） level and change of patients with bone neoplasms within 30 day after surgery,and the correlation with post-traumatic stress（PTS） after surgery. Methods A prospective cohort study was conducted by convenience sampling to select patients who met the criteria for inclusion and exclusion in the orthopedic ward of a tertiary hospital in Sichuan Province. The cohort was divided based on the scores of the revised version of Chinese translation of the Impact of Event Scale-Revised for patients 2 days after surgery. Patients whose scores were≥26 points would be included in the larger PTS group,and <26 points would be included in the smaller PTS group. Their PTG levels were assessed at 2nd day,15th day,and 30th day after surgery. Results In the end,a total of 142 cases were included. 78 cases were included in the smaller PTS group and 64 cases in the larger PTS group. The differences in PTGI-C scores of all patients at 2 d,15d and 30 d after surgery were no statistically significant. The PTGI-C scores of the patients in the smaller group of PTS were 34.95±25.60,31.96±22.20,and 37.77±25.32 at 2 d,15 d,and 30 d after the operation（F=2.704,P=0.069）. The scores of the patients in the larger PTS group at each time point after the operation were 53.48±17.70,48.78±21.47 and 50.84±22.80 points（F=27.029,P<0.001）. The difference in PTG levels between the 2 groups at each time point was statistically significant. Multiple linear regression results suggest that postoperative 2 d PTS has a statistically significant effect on postoperative 30 d PTG（β=0.272,P<0.05）. Conclusion The lowest point of PTG within 30 days after surgery is 15 days after surgery. Therefore,at this time,medical staff should promptly identify people at risk of reduced PTG and carry out targeted interventions. When the PTS caused by the surgical event gets stronger,the PTG level will be higher. There is a positive correlation between them.

Objective To evaluate the effect of aerobic combined resistance exercise in children with malignant tumors. Methods We searched databases including Wanfang,VIP,CNKI,CBM,Web of Science,Cochrane Library,PubMed,Embase and CINAHL,from inception to May 2021,and we included randomized controlled trials（RCTs） reporting the effectiveness of aerobic combined resistance exercise in children with malignant tumors. 2 trained researchers screened the literature,evaluated the quality and extracted the data independently,and the meta-analysis was implemented with RevMan 5.4. Results Totally 7 RCTs involving 452 children were included. The results of meta-analysis showed that after exercise intervention,the cancer-related fatigue[SMD=-1.07,95%CI（-1.60,-0.53）,P<0.01] and 6-minute walk test[SMD=0.83,95%CI（0.47,1.19）,P<0.01] of children in the experimental group are better than those in the control group. There were no statistically significant differences in peak oxygen uptake [SMD=-0.08,95%CI（-0.42,0.26）,P=0.63] and health-related quality of life[SMD=-0.09,95%CI（-0.44,0.26）,P=0.62]. Conclusion Aerobic combined with resistance exercise can alleviate cancer-related fatigue in children with malignant tumors and enhance their cardiopulmonary function. However,the conclusion of this study needs to be confirmed by further high quality research.